Shodex Polymer-Based Columns – Reversed Phase Chromatography
Shodex Reversed-Phase HPLC Columns are packed with porous polymeric material that remains stable across a pH range of 2–12.
These columns offer an alternative selectivity to the silica-based columns.
The Asahipak ODP-50 series, which features C18 functional groups and is commonly used for analyzing non-polar substances in pharmaceuticals, food, and biological samples.
Additionally, Shodex offers other polymer-based reversed phase columns without C18 groups, such as the RSpak DE, DM, and DS series, which cater to specific analytical needs.
These columns are usable in a wide pH range from pH 2 to 12 and can be employed with ELSD, CAD, and MS/MS detection methods.
The ODP-50 series fulfills USP L67 requirements, making it a reliable choice for various applications.
For those seeking extra small pore sizes, the RSpak DE-213, DE-413, and DE-613 columns are suitable for analyzing vitamins, preservatives, and organic acids.
מידע נוסף
Asahipak ODP-50 series
Polymer-based column with C18 functional groups
- For pharmaceuticals and food applications
- Large pore size suitable for analyzing amino acids, peptides, and proteins
- Operates effectively across a wide pH range of 2 to 13
- Compatible with 100% water and buffer solutions
- Optimal for analyzing basic substances
- Recommended for ELSD, CAD, and MS/MS detection
- ODP-50 meets USP L67 standards
RSpak DE, DM and DS columns
Polymer-based reversed phase columns without C18 groups
RSpak DE-213, DE-413, and DE-613
- Wide pH range usability (from pH 2 to 12), suitable for 100% water and buffer solutions
- Extra small pore size of 25 Å
- Ideal for analyzing vitamins, preservatives, and organic acids
- Meets USP L71 requirements (polymethacrylate particles)
RSpak DM-614
- Perfect for the analysis of amino acids and water-soluble vitamins
- pH range from 2 to 10
- Complies with USP L39 requirements (polyhydroxymethacrylate particles)
RSpak DS-413 and DS-613
- Suitable for reversed phase analysis of highly hydrophilic substances that are poorly retained by ODS columns
- Meets USP L21 requirements (styrene divinylbenzene copolymer particles)
RSpak NN and JJ columns
Polymer-based multi mode columns with reversed phase and ion exchange chromatography
RSpak NN-814
- Modified with sulfo groups to support multimode analysis (reversed phase and cation exchange)
- Ideal for analyzing complex samples containing both neutral and ionic substances
- Suitable for separating water-soluble compounds such as nucleotides, nucleosides, nucleobases, water-soluble vitamins, and amino acids
RSpak JJ-50 2D
- Modified with trace amounts of quaternary ammonium groups, enabling multimode analysis (reversed phase and anion exchange)
- Perfect for analyzing complex samples that contain neutral and ionic substances
ODP2 series
New generation of polymer-based reversed phase columns
- Higher polarity compared to traditional RP columns
- Enhances retention of polar and basic substances
- Suitable for small molecules in protein matrices
- Free of silanol groups, preventing adsorption
- Ideal for LC-MS/MS applications
- Offers true pH stability
Silica C18 columns
Classic reversed phase columns with C18 groups
Silica C18M
- Designed for HPLC applications
- Fully end-capped ODS column
- Meets USP L1 requirements
Silica C18U
- Designed for UHPLC applications
- Provides high-performance analysis with sub-2 µm particles
- Hybrid organic/inorganic silica particles for enhanced alkali durability (pH 1 to 12)
- Suitable for use in 100% water and buffer solutions
- Meets USP L1 requirements
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עמודות Shodex Reversed-Phase על בסיס פולימר
מה היתרון של עמודת reversed-phase על בסיס פולימר?
Polymer-based RP columns (e.g. Shodex Asahipak/RSpak) are stable across a very wide pH range (typically pH 1–13) versus silica, so they suit basic compounds, harsh conditions and CIP cleaning. Choose them when pH stability and chemical durability are critical.
נכתב ונבדק על ידי Dani Shahar וצוות היישומים של BioAnalytics · יבואן Shodex בישראל