Shodex Polymer-Based Columns – Reversed Phase Chromatography

Shodex Reversed-Phase HPLC Columns are packed with porous polymeric material that remains stable across a pH range of 2–12.
These columns offer an alternative selectivity to the silica-based columns.

The Asahipak ODP-50 series, which features C18 functional groups and is commonly used for analyzing non-polar substances in pharmaceuticals, food, and biological samples.

Additionally, Shodex offers other polymer-based reversed phase columns without C18 groups, such as the RSpak DE, DM, and DS series, which cater to specific analytical needs.

These columns are usable in a wide pH range from pH 2 to 12 and can be employed with ELSD, CAD, and MS/MS detection methods.

The ODP-50 series fulfills USP L67 requirements, making it a reliable choice for various applications.

For those seeking extra small pore sizes, the RSpak DE-213, DE-413, and DE-613 columns are suitable for analyzing vitamins, preservatives, and organic acids.

מידע נוסף

Asahipak ODP-50 series

Polymer-based column with C18 functional groups

  • For pharmaceuticals and food applications
  • Large pore size suitable for analyzing amino acids, peptides, and proteins
  • Operates effectively across a wide pH range of 2 to 13
  • Compatible with 100% water and buffer solutions
  • Optimal for analyzing basic substances
  • Recommended for ELSD, CAD, and MS/MS detection
  • ODP-50 meets USP L67 standards

RSpak DE, DM and DS columns

Polymer-based reversed phase columns without C18 groups

RSpak DE-213, DE-413, and DE-613

  • Wide pH range usability (from pH 2 to 12), suitable for 100% water and buffer solutions
  • Extra small pore size of 25 Å
  • Ideal for analyzing vitamins, preservatives, and organic acids
  • Meets USP L71 requirements (polymethacrylate particles)

RSpak DM-614

  • Perfect for the analysis of amino acids and water-soluble vitamins
  • pH range from 2 to 10
  • Complies with USP L39 requirements (polyhydroxymethacrylate particles)

RSpak DS-413 and DS-613

  • Suitable for reversed phase analysis of highly hydrophilic substances that are poorly retained by ODS columns
  • Meets USP L21 requirements (styrene divinylbenzene copolymer particles)

RSpak NN and JJ columns

Polymer-based multi mode columns with reversed phase and ion exchange chromatography

RSpak NN-814

  • Modified with sulfo groups to support multimode analysis (reversed phase and cation exchange)
  • Ideal for analyzing complex samples containing both neutral and ionic substances
  • Suitable for separating water-soluble compounds such as nucleotides, nucleosides, nucleobases, water-soluble vitamins, and amino acids

RSpak JJ-50 2D

  • Modified with trace amounts of quaternary ammonium groups, enabling multimode analysis (reversed phase and anion exchange)
  • Perfect for analyzing complex samples that contain neutral and ionic substances

ODP2 series

New generation of polymer-based reversed phase columns

  • Higher polarity compared to traditional RP columns
  • Enhances retention of polar and basic substances
  • Suitable for small molecules in protein matrices
  • Free of silanol groups, preventing adsorption
  • Ideal for LC-MS/MS applications
  • Offers true pH stability

Silica C18 columns

Classic reversed phase columns with C18 groups

Silica C18M

  • Designed for HPLC applications
  • Fully end-capped ODS column
  • Meets USP L1 requirements

Silica C18U

  • Designed for UHPLC applications
  • Provides high-performance analysis with sub-2 µm particles
  • Hybrid organic/inorganic silica particles for enhanced alkali durability (pH 1 to 12)
  • Suitable for use in 100% water and buffer solutions
  • Meets USP L1 requirements

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