Shodex SUGAR Columns – Ligand Exchange Chromatography

Shodex SUGAR Columns
Ligan Exchange Chromatography -

HPLC-based saccharide and sugar alcohol analyses use various modes, including HILIC, ligand exchange, size exclusion, and ion exchange.

The Shodex SUGAR series columns feature a styrene-divinylbenzene copolymer base and a strong cation exchange resin with sulfo-groups and metal counter ions. These columns come in various types, offering different selectivity based on counter ion, pore size, and structure.

Ideal for saccharide separation and analysis in food science, biochemistry, and natural substance research, the series includes Asahipak GS-220 HQ for low molecular weight dietary fibers and OHpak SB-800 HQ for polysaccharides.

A key feature is the ligand exchange separation mechanism, where hydroxyl groups and metal ions interact to form complexes.

SUGAR SP0810

Ligand exchange column with lead (Pb2+) counter ions

For sugar analysis
Separates saccharides through a combination of ligand exchange and size exclusion modes
Requires only water for the analysis of neutral sugars
meets USP L22 and L34 standards
Primarily used for routine quality control in food analysis.

SUGAR SC1011 and SUGAR SC1211

Columns with calcium (Ca2+) counter ions

SUGAR SC1011

For saccharide analysis using ligand exchange mode
Only water (or Ca-salt solution) is required for the analysis of neutral sugars
Fulfills USP L19 and L22 requirements

SUGAR SC1211

Combination of ligand exchange and HILIC modes
Suitable for separating sugar alcohols
Fulfills USP L19 and L22 requirements

SUGAR KS-800 series

Columns with sodium (Na+) counter ions

Separates saccharides using a combination of ligand exchange and size exclusion modes
Requires only water for analyzing neutral sugars
Ideal for polysaccharide separation via size exclusion mode
Can be used in series (2-3 columns in a row with the same or different exclusion limits)
Meets USP L22 and L58 standards