Solid sample loading is a great way to perform more efficient and consistent flash chromatography.  With solid loading you can eliminate the effects of injection volume and solvent on your Flash chromatography. Teledyne ISCO Flash chromatography solid sample load cartridges are designed to take advantage of this technique, as outlined in several application notes on the subject, and in our how-to video series​ . Solid sample loading however does require the extra step of either adsorbing your compound to the silica before loading the cartridge, or applying it to a prepacked solid-load cartridge and allowing it to dry to evaporate the solvent.